Cold-pressed sesame oil is a good source of vitamin E, containing 11.8 mg of the vitamin for every 100 g of the oil. Vitamin E gives sesame oil its antioxidant property. It also has a high concentration of fatty acids, including polyunsaturated omega-6 fatty acids and monounsaturated omega-9 fatty acids. Other constituents of cold-pressed sesame oil include zinc, copper, magnesium, calcium and iron as well as vitamin B-6. Zinc contributes to healthy bones.

Cold-pressed sesame oil is known in Ayurvedic practice as the healing oil. When applied topically to the skin or hair, its antibacterial, antiviral and anti-inflammatory properties provide protective, nourishing and detoxifying effects on stressed and damaged skin. The high concentration of omega-6 fatty acids in cold-pressed sesame oil makes it a moisturizing and an ideal massage oil. Sesame oil also rejuvenates the skin and prevents premature aging. It is especially useful for dry and damaged skins as well as in the treatment of sunburn, skin allergies, chemical burns, eczema, rosacea, dry hair and dandruff.